This might be for you if you notice
- Memories or dreams that keep returning and disturb your rest
- Staying away from places or conversations that bring reminders
- Feeling tense, on guard or easily startled long after you are safe
- Wanting to understand your options before choosing a treatment
- Wondering whether medication, therapy or both could fit you
- Taking a medicine for PTSD and having questions about it
What treatment for PTSD involves
After a traumatic event, most people recover from early reactions over time. The National Institute of Mental Health (NIMH) says people whose symptoms continue may be diagnosed with post-traumatic stress disorder (PTSD), and that you can get better with treatment. The main treatments are psychotherapy, medication, or a combination.
You do not have to describe what happened in detail to learn your options. This page explains the talk therapies and the medicine groups in the 2023 VA/DoD Clinical Practice Guideline, written by the U.S. Departments of Veterans Affairs and Defense. In its wording, "we recommend" is a strong recommendation and "we suggest" is a weak one.
The guideline's first treatment-selection statement is: "We recommend individual psychotherapies, listed in Recommendation 8, over pharmacologic interventions for the treatment of PTSD." That is rated Strong for. The National Center for PTSD adds that medication is an effective option when those therapies are not available or feasible, or when a person prefers medication.
Therapy approaches, and what each one is
"Trauma-focused" means the therapy centers on the memory of the event and what it means to you. The guideline sorts talk therapies by the strength of its recommendation:
- Recommended (Strong for): Cognitive Processing Therapy, which works on upsetting thoughts and feelings since the trauma; Prolonged Exposure, which gradually approaches memories, feelings and situations you have been avoiding; and Eye Movement Desensitization and Reprocessing (EMDR), which processes the memory while you attend to a back-and-forth movement or sound.
- Suggested (Weak for): Ehlers' Cognitive Therapy for PTSD, Present-Centered Therapy, which focuses on current problems rather than the trauma, and Written Exposure Therapy, which uses writing during sessions.
- Insufficient evidence to recommend for or against: a longer list that includes Accelerated Resolution Therapy (ART) and Dialectical Behavior Therapy.
Medicine groups, and where each stands
Only sertraline and paroxetine are FDA-approved for PTSD, and every other use for PTSD is off-label. A guideline recommendation and an FDA approval are separate things, so both are shown here.
- SSRIs (antidepressants that act on serotonin): sertraline and paroxetine are FDA-approved for PTSD and recommended (Strong for). The guideline finds insufficient evidence to recommend for or against citalopram, escitalopram and fluoxetine.
- SNRIs (antidepressants that act on serotonin and norepinephrine): venlafaxine is off-label for PTSD and recommended (Strong for). Evidence is insufficient to recommend for or against desvenlafaxine and duloxetine.
- Alpha-blocker: prazosin is an off-label blood pressure medicine. The guideline suggests it for nightmares associated with PTSD (Weak for) and suggests against it for PTSD overall (Weak against).
- Benzodiazepines: the guideline recommends against them for PTSD (Strong against). If you take one, keep working with your prescriber and do not stop suddenly.
- Antipsychotics: the guideline suggests against adding any of a listed group to medications for PTSD (Weak against), and suggests against risperidone for PTSD. Evidence is insufficient to recommend for or against olanzapine or quetiapine for PTSD.
- Mood stabilizers: it suggests against divalproex and tiagabine (Weak against), and finds insufficient evidence to recommend for or against lamotrigine or topiramate.
Risks to know about medicine
The labels for sertraline and paroxetine carry a boxed warning, the FDA's most prominent kind: antidepressants increased the risk of suicidal thoughts and behaviors in children, teens and young adults, and everyone taking them should be watched closely for worsening. Those labels also say not to combine them with MAOIs, a group of medicines, and to reduce the dose gradually rather than stopping abruptly whenever possible.
If you are in crisis or thinking of harming yourself, call or text 988, or call 911. Locascio Wellness does not provide emergency services. No medicine here is a recommendation for you. Whether it is an option for you is a decision for you and your prescriber. Ask us whether our psychiatrist can help.
Who you can see here, and where
Medication care: a licensed psychiatrist on our team, a Doctor of Osteopathic Medicine with more than three decades of practice, treats anxiety, depression and trauma by secure video. You must be physically located in Pennsylvania or New York during each visit. Read more about medication management. Our therapists do not prescribe.
Therapy: trauma therapy with our team is for clients physically located in Pennsylvania, West Virginia, Arizona or Colorado. New York readers can see our psychiatrist here, but not a therapist here. Services differ by state, so check our trauma and PTSD therapy page or ask what is available where you live. Members of the team use approaches including EMDR, ART and trauma-focused CBT. Not every therapist uses every approach, so ask which one yours uses.
Getting started
- Reach outSend us a note through our medication care contact form or call 267-573-9817, and tell us which state you will be in during visits.
- Ask your practical questionsAsk us about fees, insurance for psychiatry, ages seen and timing, and whether therapy here is required.
- Meet by videoFrom a private spot, talk through your history and goals. You choose how much to share, and a visit may or may not lead to a prescription.
Your psychiatrist
Psychiatric care here is with our psychiatrist, licensed as a physician in Pennsylvania and New York. His license details are on his profile.
Medicines you may hear about for trauma
Some are FDA-approved for it and some are used off-label; each page says which, and lists its warnings. Whether any of them is right for you is a decision for you and your prescriber.
- Sertraline (Zoloft)
- Fluoxetine
- Paroxetine (Paxil)
- Venlafaxine (Effexor XR)
- Prazosin
Guides
Ready to start
- How to Get PTSD Medication Care Online in PennsylvaniaSteps for seeking PTSD medication care online in Pennsylvania: who licenses physicians, how to check a license, and how to reach our psychiatrist by secure video.Read article
- How to Get PTSD Medication Care Online in New YorkSteps for seeking PTSD medication care online in New York: NYSED license checks, Department of Health records, and reaching our psychiatrist by secure video.Read article
- Your First Online Psychiatry Visit for Trauma: What to ExpectWhat a first online psychiatry visit for trauma can be like: you choose how much to share, what may be asked, and why it may not end in a prescription. PA and NY.Read article
- Finding an Online Psychiatrist for Trauma: Questions and ChecksHow to find an online psychiatrist for trauma: questions to ask, how to check a license in Pennsylvania or New York, and how to coordinate with a therapist.Read article
Comparing your options
- PTSD Medication vs. Trauma Therapy: What the Guidance SaysWhat the VA/DoD guideline and NIMH say about trauma-focused therapy and medication for PTSD, and how care works online in Pennsylvania and New York with us.Read article
- SSRIs and Venlafaxine for PTSD: Guideline and Label FactsWhat the VA/DoD guideline and FDA labels say about sertraline, paroxetine and venlafaxine for PTSD, what is off-label, and online care in PA and New York.Read article
- Taking Medication During EMDR or Trauma TherapyTaking medication during EMDR or trauma therapy: telling both clinicians, coordinating care and what guidance says, with online care in PA and New York.Read article
- Medication When PTSD and Depression Occur TogetherPTSD and depression often appear together. General information on medicine, safety and coordinating care, with online psychiatry in Pennsylvania and New York.Read article
Support and resources
- Medications for PTSD: An Overview of the Main GroupsAn overview of medicine groups used or studied for PTSD, what the VA/DoD guideline says about each, and how online care works in Pennsylvania and New York.Read article
- Which PTSD Medications Are FDA-Approved?As of November 2026, which medicines have an FDA PTSD indication on their labels, what off-label means, and how online care works in Pennsylvania and New York.Read article
- Prazosin for PTSD Nightmares: What the Guideline and Label SayPrazosin for PTSD nightmares is off-label. What the VA/DoD guideline says, plus blood pressure and fainting risks, and online care in Pennsylvania and New York.Read article
- Why Benzodiazepines Are Not Recommended for PTSDThe VA/DoD guideline recommends against benzodiazepines for PTSD. Why, what to do if you take one, and online psychiatry for people in Pennsylvania and New York.Read article
Questions people ask
Is trauma treatment online an option?
Yes, it can be. The VA/DoD guideline recommends secure video (Strong for) to deliver its listed therapies when the therapy has been validated by video or when other options are unavailable. It notes that this recommendation is specific to Cognitive Processing Therapy and Prolonged Exposure as tested by video. Ask how a treatment works by video.
Do I have to talk about what happened?
That depends on the treatment. Trauma-focused therapies work with the memory and what it means to you. The National Center for PTSD says Present-Centered Therapy is non-trauma-focused, so you do not need to focus on your traumatic experience. At a psychiatry visit here, you choose how much to share, and you can say so at any point.
Can I get therapy here if I live in New York?
Not at this time. Trauma therapy with our team is available in Pennsylvania, West Virginia, Arizona and Colorado. If you are physically in New York during visits, you can ask about seeing our psychiatrist, and you can look for a New York licensed therapist elsewhere. With your permission, your prescriber and therapist can share information.
Which medicines are FDA-approved for PTSD?
As of November 2026, sertraline and paroxetine. The Paxil label lists PTSD in adults and the Zoloft label lists PTSD, and the National Center for PTSD says all other medication uses for PTSD are off-label. The VA/DoD guideline also recommends venlafaxine, which is off-label for PTSD. Choosing among them is a decision for you and a prescriber.
Does insurance cover online psychiatry for PTSD?
Please ask us. Coverage for psychiatry visits depends on your plan, and we cannot state it on this page. When you contact us, share your plan and the state you will be in during visits, and ask what your costs may be before you decide to book anything with our team.
How do online visits work?
You meet by secure video on a phone, tablet or computer, from a private place with a steady internet connection. You must be physically in Pennsylvania or New York during each psychiatry visit. Keep a list of your medicines and your questions close by, and tell us if you would like a therapist involved.
Sources
- VA/DoD Clinical Practice Guideline for the Management of Posttraumatic Stress Disorder and Acute Stress Disorder (2023)
- National Center for PTSD: Clinician's Guide to Medications for PTSD
- National Institute of Mental Health: Post-Traumatic Stress Disorder
- National Center for PTSD: Talk Therapy
- DailyMed: Zoloft (sertraline) prescribing information
- DailyMed: Paxil (paroxetine) prescribing information
Published by Locascio Wellness. Last updated October 9, 2026. Clinically reviewed by Kenneth M. Levy, DO, Psychiatrist (Pennsylvania license OS007464L). This page is general information, not medical advice or a diagnosis.
